Journal of the American Chemical Society, Vol.131, No.31, 10848-10848, 2009
Total Synthesis and Structural Revision of (+/-)-Tricholomalides A and B
The neurotrophic diterpenoids, tricholomalides A and B, were synthesized in a concise fashion. Key transformations include a ketene [2 + 2] cycloaddition and a Grignard-type reaction. In the course of the synthesis, it was determined that the structures of tricholomalides A and B had originally been misassigned.