Recently, the new optics design offers the key to expand the de(p)olarized striall-angle light scattering (SALS) technique into complicated aggregation systems. We try to establish methodological basis especially for depolarized (H-nu) scattering as applied to the recent advances in soft matter science. We give the scaled form factor (P) over bar (H nu)(x) to study the universal feature of the H-nu scattering from a birefringent sphere in nucleation and growth process. On the other hand, lacking the ability to describe the global-structure evolution, the structure factor scaling in aggregation and coarsening process of birefringent spheres are unsatisfactory for H-nu scattering. However, the H-nu and V-nu (polarized) scattering complement each other well, for each captures a different aspect of the structural evolution of scatterers. The H-nu scattering highlights the feature of the local-structure evolution; in contrast, the V-nu, scattering relates mainly to the feature of long-range fractal structure of aggregates. In order to understand the birefringence decline in a growing birefringent sphere, the two categories of birefringent sphere are considered, namely the crystallographic disorder (category 1) and the aggregation of crystallitic grains (category 2), and the PVDF microgel belongs to the category 2 and may be regarded as "soft colloids".