The anion exchange chromatographic technique has been employed for the separation of Pb(II), from some divalent and trivalent metal ions using Dowex 2-X8 exchange resin (nitrate form). The effect of metal ion concentration on the distribution coefficients (K-d) have been investigated and a suitable media is selected. The batch distribution coefficient has been determined for Mg(II), Co(II), Fe(III), Cd(II) and Pb(II) ions using different concentrations of nitric acid and different proportions of ethanol and acetone. The results showed that lead is adsorbed much more strongly in the exchanger used than the most other elements.