Membrane separation is one of the most used processes at present but its long term application is still limited because of concentration polarization and fouling caused by particles which are retained by the membrane. These retained particles accumulate on the membrane surface or/and in the pores and result in reducing the membrane porosity and increasing the overall membrane resistance. The net effect is decrease in the permeation rate with process time. In case where the treatment of the feed or the membrane is not feasible or advisable, hydrodynamic methods can be used for controlling the concentration polarization and membrane fouling. In this paper, various hydrodynamic systems developed and tested for the control of permeate flux decrease or for its enhancement have been reviewed. Using polypropylene and polyamide hollow fibre filters for plasma separation, it is shown that appropriate pulsations applied to the inlet blood flow could enhance the filtration rate by about 45% compared to nonpulsatile conditions. When a rotating membrane device equipped with polycarbonate membrane for separating plasma from whole blood was used, it has been found that the filtration velocities were 10-20 times higher than those obtained with steady flow. With tubular mineral membranes (ceramic and carbon) for raw apple juice and raw wine clarification, when pressure and flow pulsations have been superimposed on the inlet flow of the filtration module, that the permeate flux increased up to 45% at 1 Hz frequency and with stroke volumes smaller than the internal volume of the membrane. Carefully chosen pulsations wave form decreased the hydraulic power dissipated in the retentate per unit volume of permeate up to 30%. The use of a helical shape baffle in a mineral membrane for microfiltration of bakers yeast solution (5% dry weight) and dodecane-water emulsion (0.1% by weight) provided an increase of more than 50% in permeate flux compared to that obtained without a baffle at the same hydraulic dissipated power.