We exposed a novel method by using DNA as the dopant as well as template at the same time to prepare PANI-DNA hybrid micro/nanowires with conductivity as high as similar to 10(-2) S cm(-1). The high conductivity is due to the co-doping function of DNA with HCl produced by FeCl3. It is found that the morphology and conductivity of the PANI-DNA hybrids are affected by the [DNA]/[AN] ratio due to the co-operation and competition of DAN's dopant and template function, and the role of DNA in PANI-DNA hybrid varies with the changing of [DNA/[AN] ratios. (C) 2009 Elsevier Ltd. All rights reserved.