The effect of surface roughness on particle-wall interaction was studied by the airflow method. Five kinds of monodispersed spherical particles (Dp(50)= 11-41 mu m) and six test pieces with different surface roughness (Ra=0.01-1.64 mu m) were used in the experiments. The particles were dispersed on the test pieces to form a monolayer, and entrained in a rectangular air channel. The air velocity increased at a constant rate, and the entrained particles were detected with a laser dust Monitor. Microscopic observations showed that particle entrainment occurred in discrete and intermittent events during experiment, thus a statistical parameter, i.e. the particle entrainment efficiency as a function of the air velocity, was defined for evaluating the particle-wall interaction force distribution. The experimental results showed that the air velocity for particle entrainment decreases with the increase of the surface roughness within submicron-scale and reaches a lower limit, while increases to some extent for micronscale surface roughness. It was also found that the effect of the Substrate Surface roughness depends on the particle diameter. (c) 2007 Elsevier B.V. All rights reserved.