Learning from nature has inspired the creation of intelligent materials to better understand and imitate biology. Recent studies on bioinspired responsive surfaces that can switch between different states are shown, which open up new avenues for the development of smart materials in two dimensions. Based on this strategy, biomimetic nanochannel systems have been produced by introducing responsive molecules, which closely mimic the gating mechanism of biological nanochannels and show potential applications in many fields such as photoelectric-conversion systems demonstrated in this paper.