Aligned straight and wavy fibers of biodegradable poly(D,L-lactic-co-glycolic acid) (PLGA) are fabricated using a magnetic-field-assisted electrospinning method. PLGA fibrous matrices prepared by this method can guide the growth of pluripotent murine mesenchymal stem cells. While the stem cells on the randomly oriented fibers adapt pseudo-sphere-like shape, those on aligned fibers exhibit elongated morphology along the long axes (see figure).