Conversion, selectivity and yield of 1-hexanol liquid phase dehydration to di-n-hexyl ether (DNHE) were determined at 150-190 degrees C on three acidic catalysts, the thermally stable resin Amberlyst 70, the perfluoroalkanesulfonic Nafion NR50 and the zeolite H-BEA-25, in a batch reactor. The highest conversion and yield were achieved on Amberlyyst 70 at 190 degrees C, but the most selective catalyst was Nafion NR50. Good results were obtained at 190 degrees C on the zeolite. Apparent activation energies for the three catalysts were in the range 108-140 kJ/mol. Unlike H-BEA-25, the reaction of DNHE synthesis on Amberlyst 70 and NR50 was a bit more active but less selective than the analogous 1-pentanol dehydration to di-n-pentyl ether (DNPE). (c) 2009 Elsevier B.V. All rights reserved.