SEPARATION OF CLOSE-BOILING COMPONENTS BY THE COMBINED CONTINUOUS AND PREPARATIVE CHROMATOGRAPHY : COMPARISON OF EXPERIMENTAL DATA WITH CALCULATED VALUES IN BINARY SYSTEM

ROW KH; LEE YY; LEE WK

Korean Journal of Chemical Engineering, Vol.7, No.3, 210-218, July, 1990

ROW KH, LEE YY, LEE WK

Operational characteristics of the combined continuous and preparative gas-liquid chromatographic system were investigated for the separation of two close-boiling components, diethylether and dichloromethane. It was experimentally confirmed that the additional column length and the desorbent velocity were the most important factors to ensure the continuous separation of the feed mixture.
The theoretical concentration profiles derived with the assumptions of the uniform film thickness and linear partition equilibrium were in relatively good agreement with the experimental data for the combined continuous and preparative chromatographic system, and it could be used as a powerful predictive tool for determining the optimum operating conditions.

[References]

Bonmati RG, Chapelet-Letourneux G, Margulis JR, Chem. Eng., 87, 70 (1989)
Barker PE, "Developments in Chromatography," Knapman, C.H. (editor), Applied Science Publishers, London (1978)
Grushka E, "Preparative-Scale Chromatography," Marcel Dekker, Inc., New York and Basel (1989)
Row KH, Ph.D. Thesis, Korea Advanced Institute of Science & Technology, Seoul (1986)
Row KH, Lee WK, "Separation by Gasliquid Chromatography," Cheremisinoff, N.P., (Editor), Handbook of Heat and Mass Transfer, Vol. 3: Catalysis, Kinetics, and Reactor Engineering, Chapter 22, Gulf Publishing Company, Houston (1989)
Row KH, Lee WK, Sep. Sci. Technol., 22, 1761 (1987)
Broughton DB, Chem. Eng. Process., 64, 60 (1969)
Ching CB, Ruthven DM, Chem. Eng. Sci., 40, 1411 (1985)
Fish BB, Carr BW, Aris R, AIChE J., 35, 737 (1989)
Row KH, Lee WK, J. Chem. Eng. Jpn., 19, 173 (1986)
Alkarasani MA, McCoy BJ, Chem. Eng. J., 23, 81 (1982)
Dang NDP, Gibilaro LG, Chem. Eng. J., 8, 157 (1974)
Moon I, Row KH, Lee WK, Korean J. Chem. Eng., 2(2), 155 (1985)
McNair HM, Bonelli AJP, "Basic Gas Chromatography," Varian Aerograph, Berkeley (1969)
Littlewood A, "Gas Chromatography," Academic Press, New York (1970)
James AT, Martin AJP, Analyst, 77, 915 (1952)
Row KH, Chromatographia, 25, 961 (1988)

[1] Bonmati RG, Chapelet-Letourneux G, Margulis JR, Chem. Eng., 87, 70 (1989)

[2] Barker PE, "Developments in Chromatography," Knapman, C.H. (editor), Applied Science Publishers, London (1978)

[3] Grushka E, "Preparative-Scale Chromatography," Marcel Dekker, Inc., New York and Basel (1989)

[4] Row KH, Ph.D. Thesis, Korea Advanced Institute of Science & Technology, Seoul (1986)

[5] Row KH, Lee WK, "Separation by Gasliquid Chromatography," Cheremisinoff, N.P., (Editor), Handbook of Heat and Mass Transfer, Vol. 3: Catalysis, Kinetics, and Reactor Engineering, Chapter 22, Gulf Publishing Company, Houston (1989)

[6] Row KH, Lee WK, Sep. Sci. Technol., 22, 1761 (1987)

[7] Broughton DB, Chem. Eng. Process., 64, 60 (1969)

[8] Ching CB, Ruthven DM, Chem. Eng. Sci., 40, 1411 (1985)

[9] Fish BB, Carr BW, Aris R, AIChE J., 35, 737 (1989)

[10] Row KH, Lee WK, J. Chem. Eng. Jpn., 19, 173 (1986)

[11] Alkarasani MA, McCoy BJ, Chem. Eng. J., 23, 81 (1982)

[12] Dang NDP, Gibilaro LG, Chem. Eng. J., 8, 157 (1974)

[13] Moon I, Row KH, Lee WK, Korean J. Chem. Eng., 2(2), 155 (1985)

[14] McNair HM, Bonelli AJP, "Basic Gas Chromatography," Varian Aerograph, Berkeley (1969)

[15] Littlewood A, "Gas Chromatography," Academic Press, New York (1970)

[16] James AT, Martin AJP, Analyst, 77, 915 (1952)

[17] Row KH, Chromatographia, 25, 961 (1988)