Selective catalytic reduction (SCR) of NO with NH3 over manganese substituted iron titanate catalysts was fully studied. The low temperature SCR activity was greatly enhanced when partial Fe was substituted by Mn, although the N-2 selectivity showed some decrease to a certain extent. The Mn substitution amounts showed obvious influence on the catalyst structure, redox behavior and NH3/NOx adsorption ability of the catalysts. Among FeaMn1-aTiOx (a = 1, 0.75, 0.5, 0.2, 0) serial catalysts, Fe0.5Mn0.5TiOx with the molar ratio of Fe:Mn = 1: 1 showed the highest SCR activity, because the interaction of iron, manganese and titanium species in this catalyst led to the largest surface area and the highest porosity, the severest structural distortion and most appropriate structural disorder, the enhanced oxidative ability of manganese species, the highest mobility of lattice oxygen, the proper ratio of Bronsted acid sites and Lewis acid sites together with the enhanced NOx adsorption capacity. (C) 2009 Elsevier B.V. All rights reserved.