Several new materials and patterns are studied for the formation and etching of intraocular lenses (IOLs), in order to improve their optical properties, to reduce the diffractive aberrations and to decrease the incidence of posterior capsular opacification. The aim of this study is to investigate the use of UV (lambda = 266 nm) laser pulses to ablate the intraocular lenses materials, and thus to provide an alternative to conventional surface shaping techniques for IOLs fabrication. Ablation experiments were conducted using various polymer substrates of hydrophobic acrylic IOLs and PMMA IOLs. We investigated the ablation efficiency and the morphology of the ablated area by imaging the surface modi. cation with atomic force microscopy (AFM) and scanning electron microscopy (SEM). The morphological appearance of IOL samples reveals the effect of a photochemical and photothermal ablation mechanism. (C) 2009 Elsevier B. V. All rights reserved.