Amino ion implantation was carried out at the energy of 80 keV with fluence of 5 x 10(15) ions cm(-2) for indium tin oxide film (ITO) coated glass, and the existence of amino group on the ITO surface was verified by X-ray photoelectron spectroscopy analysis and Fourier transform infrared spectra. Scanning electron microscopy images show that multi-wall carbon nanotubes (MWCNTs) directly attached to the amino ion implanted ITO (NH2/ITO) surface homogeneously and stably. The resulting MWCNTs-attached NH2/ITO (MWCNTs/NH2/ITO) substrate can be used as electrode material. Cyclic voltammetry results indicate that the MWCNTs/NH2/ITO electrode shows excellent electrochemical properties and obvious electrocatalytic activity towards uric acid, thus this material is expected to have potential in electrochemical analysis and biosensors. (C) 2010 Elsevier B. V. All rights reserved.