The influence of high-energy e-beam treatment at atmospheric pressure on the structure and photocatalytic activity of TiO2 was examined. Using an e-beam energy of 1 MeV and exposure in the range of 5-15 kGy, an improvement in the photocatalytic activity of TiO2 was observed. An increase in the population of C-O bonds was found in the C and O 1s states using X-ray Photoelectron Spectroscopy (XPS) suggesting that the change in the structure of the C impurities on the surface of TiO2 is closely related to the variation in the photocatalytic activity.