Fe3O4 nanoparticles-supported palladium-2, 2'-bipyridine complex was synthesized and used as catalyst for Suzuki coupling reactions between different aryl iodides and bromides with phenyl boronic acid under mild conditions. This catalyst can be separated magnetically. However, due to the aggregation of catalyst with the increase in reaction times, the activity dropped dramatically from > 99% for the first time use to 45% for the fourth time use and then kept constant subsequently.