The LCVM model (Boukouvalas et al., 1994) is applied to the prediction of vapor-liquid equilibria (VLE) for a variety of binary, ternary, and multicomponent mixtures involving gaseous components (CH4, H2S, C2H8, C3H8, and CO2) with medium and high molecular weight hydrocarbons and/or polar compounds. New interaction parameters (Ch(4)/-CH2O-, CH4/-OCCOH, and CH4/gases) are evaluated, surd some existing ones (H2S/-CH2-, CH4/ACH, CH4/ACCH(2), and C2H6/ACCH(2)) are reevaluated by using additional data. Very satisfactory results are obtained in all cases, even for asymmetric systems, where the MHV2 model (Dahl et al., 1991) fails. Of special interest are the successful results for the multicomponent systems that involve up to 24 components, including a H2S-fich sour gas mixture. LCVM is, thus, a powerful model for the prediction of VLE for a broad range of binary and multicomponent, systems.