The 5%Ni and 5%Ni-2%Au catalysts were supported on mixed oxides (MgO)(x)(Al2O3)(y). The supports were co-precipitated with molar ratio Mg/Al=0.25-2. The catalysts were studied in the partial oxidation of methane (POM). The reducibility properties, X-ray characterization, activity, selectivity and carbon resistance depending on composition of support were investigated. The highest activity (100% of CH4 conversion and 98% of CO selectivity) and stability during 72 h were achieved for 5%Ni and 5%Ni-2%Au/(MgO)(x)(Al2O3)(y). The catalysts supported on (MgO)(x)(Al2O3)(y) showed high resistance toward carbon deposition. (C) 2009 Elsevier B.V. All rights reserved.