Process intensification has long been known to be a vital concept and is considered to be one of the fundamental pillars of the chemical engineering domain. This paper reviews the advances on the high-gravity (Higee) technology, including the theoretical studies on liquid flow, gas-liquid mass transfer, residence time distribution and micromixing, and the applications of Higee technology in absorption, stripping, nanoparticles preparation and other fields such as sulfonation, polymerization, synthesis of diphenyl-methane-diisocyanate and emulsification. The application of Higee in industry shows good adaptabilities of this technology and brings considerable profits. (C) 2009 Published by Elsevier B.V.