Chemistry Letters, Vol.39, No.8, 894-895, 2010
Rhenium-catalyzed Regioselective Synthesis of Phenol Derivatives from 1,3-Diesters and Terminal Alkynes
Treatment of malonates without a substituent at the active methylene moiety with terminal alkynes gave salicylates regioselectively. In contrast, when malonates bearing a substituent at the active methylene moiety were used, cyclic,beta-keto esters were generated regioselectively. Treatment of the formed cyclic beta-keto esters with In(OTf)(3) gave phenol derivatives via decarboxylation.