화학공학소재연구정보센터
Korea-Australia Rheology Journal, Vol.22, No.4, 279-289, December, 2010
Rheological evaluation of petroleum jelly as a base material in ointment and cream formulations with respect to rubbing onto the human body
E-mail:
The objective of the present study is to systematically characterize a nonlinear viscoelastic behavior of petroleum jelly in large amplitude oscillatory shear flow fields correspondent to the rubbing condition onto the human body. With this aim, using a strain-controlled rheometer, the dynamic viscoelastic properties of commercially available petroleum jelly have been measured at 37℃ (body temperature) over a wide range of strain amplitudes at several fixed angular frequencies. In this article, the strain amplitude dependence of the dynamic viscoelastic behavior was firstly reported in detail from the experimentally obtained data and then the results were explained from a structural view-point of petroleum jelly. Nextly, a comparison of elastic and viscous properties was made in small and large strain amplitude ranges and then these results were discussed in depth with a special emphasis on their importance in actual usage situations (i.e., rubbing onto the human body or skin). Main findings obtained from this study can be summarized as follows : (1) Both the storage modulus and loss modulus show a linear behavior only within an extremely small strain amplitude range (γ0<0.2 %) and exhibit almost an equivalent strain limit of linear response (γEL=γVL=0.2 %). (2) Both the storage modulus and loss modulus demonstrate a qualitatively similar strain-dependent nonlinear behavior (i.e., strain-thinning feature), even though the storage modulus shows a stronger dependence on strain amplitude than does the loss modulus. (3) As the strain amplitude is increased, the difference between the storage modulus and loss modulus is gradually decreased and subsequently a viscous property becomes superior to an elastic property at sufficiently large strain amplitude range. (4) A large amplitude oscillatory shear flow behavior can provide a plentiful information for a better understanding of the complicated rheological behavior of semi-solid ointment-like materials in their actual application onto the human body or skin.
  1. Ahn HJ, Rheological comparison of different types of O/W emulsion.based mayonnaises : Normal, non-cholesterol and low-fat, M.E.Thesis, Pusan National University, Pusan, Korea. (2010)
  2. Ahn HJ, Song KW, Theor. Appl. Rheol., Rheological comparison of different types of mayonnaises : Normal, non-cholesterol and low-fat, 12, 71 (2008)
  3. Ahn HJ, Song KW, Theor. Appl. Rheol., Nonlinear rheology of different types of mayonnaises in several transient shear flow fields., 13, 115 (2009)
  4. Barry BW, Grace AJ, J. Texture Studies., Structural, rheological and textural properties of soft paraffins, 2, 259 (1971)
  5. Birdwell BF, Jessen FW, Nature., Crystallization of petroleum waxes, 209, 366 (1966)
  6. Boylan JC, J. Pharm. Sci., Rheological study of selected pharmaceutical semisolids, 55, 710 (1966)
  7. Brummer R, Rheology Essentials of Cosmetic and Food Emulsions, Springer-Verlag, Berlin/Heidelberg. (2006)
  8. Brummer R, Godersky S, Colloids and Surfaces A : Physicochem.Eng. Aspects., Rheological studies to objectify sensations occurring when cosmetic emulsions are applied to the skin., 152, 89 (1999)
  9. Cha MJ, Park EK, Song KW, Theor. Appl. Rheol., Rheological evaluation of pharmaceutical ointments in spreading and rubbing conditions, 13, 193 (2009)
  10. Chang GS, Large amplitude oscillatory shear flow behavior of viscoelastic polymer solutions, Ph. D. Thesis, Pusan National University, Pusan, Korea. (2010)
  11. Chang GS, Koo JS, Song KW, Korea-Aust. Rheol. J., Wall slip of vaseline in steady shear rheometry, 15(2), 55 (2003)
  12. Chang GS, Song KW, Theor. Appl. Rheol., Large amplitude oscillatory shear flow behavior of viscoelastic liquids : Fourier transform analysis, 4, 62 (2000)
  13. Cho KS, Ahn KH, Lee SJ, J. Rheol., A geometric interpretation of large amplitude oscillatory shear response, 49(3), 747 (2005)
  14. Cho KS, Song KW, Chang GS, J. Rheol., Scaling relations in nonlinear viscoelastic behavior of aqueous PEO solutions under large amplitude oscillatory shear flow, 54(1), 27 (2010)
  15. Colo SM, Herh PKW, Roye N, Larsson M, Amer. Lab., Nov., Rheology and the texture of pharmaceutical and cosmetic semisolids, 26 (2004)
  16. Davis SS, J. Pharm. Sci., Viscoelastic properties of pharmaceutical semisolids (I) : Ointment bases, 58, 412 (1969)
  17. Davis SS, J. Pharm. Sci., Viscoealstic properties of pharmaceutical semisolids (III) : Nondestructive oscillatory testing, 60, 1351 (1971)
  18. Dealy JM, Wissbrun KF, Melt Rheology and Its Role in Plastics Processing : Theory and Applications, Van Nostrand Reinhold, New York. (1990)
  19. Ewoldt RH, Hosoi AE, McKinley GH, J. Rheol., New measures for characterizing nonlinear viscoelasticity in large amplitude oscillatory shear, 52(6), 1427 (2008)
  20. Fu RCC, Lidgate DM, J. Pharm. Sci., Characterization of the shear sensitivity property of petrolatum, 74, 290 (1985)
  21. Giacomin AJ, Dealy JM, Large amplitude oscillatory shear, In Collyer, A. A. (Ed.). Techniques in Rheological Measurement, Chapman & Hall, London, pp. 99-121. (1993)
  22. Herh P, Tkachuk J, Wu S, Bernzen M, Rudolph B, Amer. Lab., The rheology of pharmaceutical and cosmetic semisolids, July, 12 (1998)
  23. Hyun K, Kim SH, Ahn KH, Lee SJ, J. Non-Newton. Fluid Mech., Large amplitude oscillatory shear as a way to classify the complex fluids, 107(1-3), 51 (2002)
  24. Hyun K, Nam JG, Wilhelm M, Ahn KH, Lee SJ, Korea-Aust. Rheol. J., Nonlinear response of complex fluids under LAOS (large amplitude oscillatory shear) flow., 15(2), 97 (2003)
  25. Kim H, Hyun K, Kim DJ, Cho KS, Korea-Aust. Rheol. J., Comparison of interpretation methods for large amplitude oscillatory shear response, 18(2), 91 (2006)
  26. Kuk HY, Large amplitude oscillatory shear flow behavior of concentrated xanthan gum solutions, M.E. Thesis, Pusan National University, Pusan, Korea. (2008)
  27. Kuk HY, Chang GS, Song KW, Theor. Appl. Rheol., Large amplitude oscillatory shear flow behavior of concentrated xanthan gum solutions : Experimental investigation and Fourier transform analysis, 10, 10 (2006)
  28. Kuk HY, Chang GS, Song KW, Theor. Appl.Rheol., Large amplitude oscillatory shear flow behavior of concentrated xanthan gum solutions : Fast Fourier transform rheology, 11, 45 (2007)
  29. Kwon MJ, Park EK, Song KW, Theor. Appl. Rheol., Nonlinear viscoelastic properties of commercial toothpastes, 13, 187 (2009)
  30. Lee KW, Park EK, Song KW, Theor. Appl. Rheol., Rheological assessment of hand lotions with respect to stability and application, 12, 151 (2008)
  31. Pandey P, Ewing GD, Drug Devel. Ind. Pharm., Rheological characterization of petrolatum using a controlled stress rheometer, 34, 157 (2008)
  32. Park EK, Rheological evaluation of semi-solid pharmaceutical ingredients, M.E. Thesis, Pusan National University, Pusan, Korea. (2008)
  33. Park EK, Song KW, Theor. Appl. Rheol., Rheological characterization of pharmaceutical and cosmetic semisolid ingredients in steady and oscillatory shear flow fields, 11, 75 (2007)
  34. Park EK, Song KW, Arch. Pharm. Res., Rheological evaluation of petroleum jelly as a base material in ointment and cream formulations : Steady shear flow behavior, 33, 141 (2010)
  35. Pena LE, Lee BL, Stearns JF, Pharm. Res., Structural rheology of a model ointment, 11, 875 (1994)
  36. Rossmurphy SB, J. Rheol., Structure-property relationships in food biopolymer gels and solutions, 39(6), 1451 (1995)
  37. Ross-Murphy SB, Shatwell KP, Biorheology., Polysaccharide strong and weak gels, 30, 217 (1993)
  38. Song KW, Chang GS, Korean J. Rheol., Nonlinear viscoelastic behavior of concentrated polyisobutylene solutions in large amplitude oscillatory shear deformation, 10(3), 173 (1998)
  39. Song KW, Chang GS, Kim CB, Lee JO, Paik JS, J. Kor. Fiber Soc., Rheological characterization of aqueous polyethylene oxide solutions (I) : Limits of linear viscoelastic response and nonlinear behavior with large amplitude oscillatory shear deformation, 33, 1083 (1996)
  40. Song KW, Kim YS, Chang GS, Fibers and Polymers., Rheology of concentrated xanthan gum solutions : Steady shear flow behavior, 7, 129 (2006)
  41. Song KW, Kuk HY, Chang GS, Korea-Aust. Rheol. J., Rheology of concentrated xanthan gum solutions : Oscillatory shear flow behavior, 18(2), 67 (2006)
  42. Wilhelm M, Macromol. Mater. Eng., Fourier-transform rheology, 287, 83 (2002)
  43. Wilhelm M, Maring D, Spiess HW, Rheol. Acta, Fourier-transform rheology, 37(4), 399 (1998)
  44. Wilhelm M, Reinheimer P, Ortseifer M, Rheol. Acta, High sensitivity Fourier-tranform rheology, 38(4), 349 (1999)
  45. Wilhelm M, Reinheimer P, Ortseifer M, Neidhofer T, Spiess HW, Rheol. Acta, The cross-over between linear and non-linear mechanical behavior in polymer solutions as detected by Fourier transform rheology., 39(3), 241 (2000)
  46. Yosick JA, Giacomin AJ, Moldenaers P, J. Non-Newton. Fluid Mech., A kinetic network model for nonlinear flow behavior of molten plastics in both shear and extension, 70(1-2), 103 (1997)
  47. Yu W, Wang P, Zhou C, J. Rheol., General stress decomposition in nonlinear oscillatory shear flow, 53, 215 (2009)