In the Republic of Croatia there are some medium temperature geothermal sources by means of which it is possible to produce electricity. However, only recently concrete initiatives for the construction of geothermal power plants have been started. Consequently, the paper provides proposals of the possible cycles for the Republic of Croatia. On the example of the most prospective geothermal source in the Republic of Croatia detailed analysis for the proposed energy conversion cycles is performed: for Organic Rankine Cycle (ORC) and Kalina cycle. On the basis of analysis results both the most suitable cycle for selected and for other geothermal sources in the Republic of Croatia are proposed. It is ORC which in case of the most prospective geothermal source in the Republic of Croatia has better both the thermal efficiency (the First Law efficiency) and the exergetic efficiency (the Second Law efficiency): 14.1% vs. 10.6% and 52% vs. 44%. The ORC gives net power of 5270 kW with mass flow rate 80.13 kg/s, while the Kalina cycle gives net power of 3949 kW with mass flow rate 35.717 kg/s. (C) 2010 Elsevier Ltd. All rights reserved.