The densities, viscosities and ultrasonic velocities for glycylglycine-NiCl2 in aqueous ethanol mixtures have been studied in the temperature range 288.15-318.15 K. The excess molar volumes, viscosity deviations and changes in isentropic compressibility for the binary mixtures have been calculated and discussed in terms of hydrogen bonding and structure-breaking effect. The computed results are fitted to the Redlich-Kister polynomial. The results clearly indicate that there is a strong association in the mixtures studied. (C) 2010 Elsevier B.V. All rights reserved.