In the present work, the zero-load plastic deformation of polydimethylsiloxane (PDMS) was examined using the nanoindentation technique. Although no load had been applied to the sample, there was an interaction between the tip and PDMS. An analysis using the power law P = a.h(n) was also performed and n values varied from 0.6 to 1.3 until they reached 1.35 for bulk PDMS. The results were compared with those obtained from the Oliver and Pharr analysis and were in good agreement. Both methods revealed the existence of a surface/near surface region (similar to 2500 nm) with enhanced elastic modulus values in comparison with those corresponding to greater penetration depths (bulk PDMS).