Laser induced opening of the C-60 cage is studied by a semiclassical electron-radiation-ion dynamics technique. The simulation results indicate that the C-60 cage is abruptly opened immediately after laser excitation. The opening of the C-60 cage induces a quick increase in kinetic energy and a sharp decrease in electronic energy, suggesting that the breaking of the C-60 cage efficiently heats up the cluster and enhances the thermal fragmentation of C-60 fullerene.