Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250 ng mL(-1) to 64 mu g mL(-1). Applicability to assay the drug in urine samples is illustrated in the concentration range 5-20 mu g mL(-1). (C) 2010 Elsevier Inc. All rights reserved.