Journal of the American Chemical Society, Vol.132, No.2, 464-464, 2010
Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to beta-Phthaliminoacrylate Esters toward the Synthesis of beta-Amino Acids
Rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to beta-phthaliminoacrylate esters took place efficiently to give high yields of beta-aryl-beta-amino acid esters with 96-99% enantioselectivity, which was realized by use of a hydroxorhodium/chiral diene complex.