Journal of the American Chemical Society, Vol.132, No.3, 916-916, 2010
Highly Efficient Cu(I)-Catalyzed Synthesis of N-Heterocycles through a Cyclization-Triggered Addition of Alkynes
An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven- membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process.