When Is the Helix Conformation Restored after the Reverse Reaction of Phototropin?

Kawaguchi Y; Nakasone Y; Zikihara K; Tokutomi S; Terazima M

Journal of the American Chemical Society, Vol.132, No.26, 8838-8838, 2010

DOI10.1021/ja1020519 Export Citation

When Is the Helix Conformation Restored after the Reverse Reaction of Phototropin?

Kawaguchi Y, Nakasone Y, Zikihara K, Tokutomi S, Terazima M

Following the disruption of the covalent bond between the cysteine and flavin of Phot1LOV2-linker, the unfolded conformation of the linker folds with a time constant of 13 ms, which is considerably (similar to 10(4) times) slower than the helix formation rate measured for an alpha-helical polypeptide in solution.