Journal of the American Chemical Society, Vol.132, No.35, 12240-12242, 2010
Catalytic Asymmetric Protonation of alpha-Amino Acid-Derived Ketene Disilyl Acetals Using P-Spiro Diaminodioxaphosphonium Barfates as Chiral Proton
Chiral diaminodioxaphosphonium salts have been developed and their unique abilities as a chiral proton have been revealed through the establishment of a highly enantioselective protonation of alpha-amino acid-derived ketene disilyl acetals.