Reduced graphene oxide (RGO)-polymer composites were prepared via pi-pi stacking interactions of RGO with the perylene bisimide-containing poly(glyceryl acrylate) (PBIPGA). PBIPGA was synthesized via atom transfer radical polymerization (ATRP) of solketal acrylate (SA), using bifunctional N,N'-bis(2-[2-[(2-bromo-2-methylpropanoyl)oxy]ethoxylethyl)perylene-3,4, 9,10-tetracarboxylic acid bisimide (PBI-Br) as the initiator, and subsequent hydrolysis of the acetal-protecting group. PBIPGA was characterized by H-1 NMR spectroscopy, gel permeation chromatography (GPC). UV-visible absorption spectroscopy and fluorescence spectroscopy. The presence of pi-pi stacking interactions between PBI and the RGO surface was suggested by fluorescence and UV-visible absorption spectroscopy results. The chemical states pi-pi interaction, morphology, and composition of RGO-PBIPGA composites were characterized, respectively, by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and thermogravimetric analysis (TGA). The low cytotoxicity level of the RGO-PBIPGA composites was revealed by incubation with 3T3 fibroblasts in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assays in vitro. (C) 2011 Elsevier Ltd. All rights reserved.