화학공학소재연구정보센터
Korean Journal of Chemical Engineering, Vol.28, No.10, 2044-2049, October, 2011
Preparation of micro particles of functional pigments by gas-saturated solution process using supercritical carbon dioxide and polyethylene glycol
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Particle design is presently a major development of supercritical fluids applications, mainly in the paint, cosmetic, pharmaceutical, and specialty chemical industries. The particles from the gas-saturated solutions (PGSS) process were used to micronize the functional compounds, fucoxanthin and astaxanthin. Fucoxanthin was extracted from brown seaweed using supercritical carbon dioxide (SC-CO2) at 20 MPa and 45 ℃. The particle formation of functional pigments with biodegradable polymer, polyethelene glycol (PEG) was performed by PGSS using SC-CO2 in a thermostatted stirred vessel. Different temperatures (40 and 50 ℃) and pressures (10-30MPa) were applied to optimize the conditions for the formation of functional pigment particles. Two nozzles of different diameter (250 and 300 μm) were used for PGSS and the reaction time was 1 hr. The average diameter of the particles obtained by PGSS at different conditions was about 0.78-1.42 μm.
  1. Nalawade SP, Picchioni F, Janssen LPBM, Chem. Eng. Sci., 62(6), 1712 (2007)
  2. Munuklu P, Jansens PJ, J. Supercrit. Fluids, 43(1), 181 (2007)
  3. Kappler P, Leiner W, Petermann M, Weidner E, Proceedings of the sixth international symposium on supercritical fluids, France, Versailles (2003)
  4. Knez Z, Proceedings of the sixth international symposium on supercritical fluids, France, Versailles (2003)
  5. Kim KY, Marshall WR Jr, AIChE J., 17, 575 (1971)
  6. Lavernia EJ, Wu J, Spray atomization and deposition, John Wiley & Sons Ltd., England (1996)
  7. Yeo SD, Kiran E, J. Supercrit. Fluids, 34(3), 287 (2005)
  8. Turk M, Lietzow R, J. Supercrit. Fluids, 45(3), 346 (2008)
  9. Yildiz N, Tuna S, Doker O, Calimli A, J. Supercrit. Fluids, 41(3), 440 (2007)
  10. Park SJ, Yeo SD, Korean J. Chem. Eng., 25(3), 575 (2008)
  11. Tandya A, Dehghani F, Foster NR, J. Supercrit. Fluids, 37(3), 272 (2006)
  12. Li G, Chu J, Song ES, Row KH, Lee KH, Lee YW, Korean J. Chem. Eng., 23(3), 482 (2006)
  13. Pathak P, Meziam MJ, Desai T, Sun YP, J. Supercrit. Fluids, 37(3), 279 (2006)
  14. Saima AL, Pharmaceutical technology biopharmaceutics, National Science Digital Library, E-book. New Delhi 110062 (2007)
  15. Weidner E, J. Supercrit. Fluids, 47(3), 556 (2009)
  16. Munuklu P, Wubbolts FE, Jansens PJ, Th W, Loos D, ‘Supercritical melt mictonisation using the PGSS process in: ACSBooks (Supercritical Carbon Dioxide), University Press, Oxford (2003)
  17. Martin A, Weidner E, J. Supercrit. Fluids, 55(1), 271 (2010)
  18. Noh MJ, Kim TG, Hong IK, Yoo KP, Korean J. Chem. Eng., 12(1), 48 (1995)
  19. Bell JB, McEvoy J, Tocher DR, Sargent JR, J. Nutr., 130, 1800 (2000)
  20. Roh MK, Uddin MS, Chun BS, Biotechnol. Bioproc. Eng., 13, 724 (2008)
  21. Wright SW, Jeffrey SW, Mantoura RFC, Llewellyn CA, Bjornland T, Repeta D, Welschmeyer N, Mar. Ecol. Prog. Ser., 77, 183 (1991)
  22. Barlow RG, Mantoura RFC, Gough MA, Fileman TW, Deep Sea Res. Part II., 40, 459 (1993)
  23. Guillou A, Choubert G, de la Noue J, Food Chem., 47, 93 (1993)
  24. de Azevedo ABA, Kieckbush TG, Tashima AK, Mohamed RS, Mazzafera P, de Melo SABV, J. Supercrit. Fluids, 44(2), 186 (2008)
  25. Lopez M, Arce L, Garrido J, Rios A, Valcarcel M, Talanta., 64, 726 (2004)
  26. Macias-Sanchez MD, Mantell C, Rodriguez M, de la Ossa EM, Lubian LM, Montero O, J. Supercrit. Fluids, 39(3), 323 (2007)
  27. Cocero MJ, Martin A, Mattea F, Varona S, J. Supercrit. Fluids, 47(3), 546 (2009)