Preparation of pore size controllable macroporous polymer beads

Juyoung Park; Yo-Han Kim; Hyo-Jin Yoon; Bong-Hyun Jun; Yoon-Sik Lee

Journal of Industrial and Engineering Chemistry, Vol.17, No.4, 794-798, July, 2011

DOI10.1016/j.jiec.2011.05.023 Export Citation

Preparation of pore size controllable macroporous polymer beads

Juyoung Park, Yo-Han Kim, Hyo-Jin Yoon, Bong-Hyun Jun^{1, †}, and Yoon-Sik Lee^†

School of Chemical and Biological Engineering, Seoul National University, San 56-1, Sillim-dong Gwanak-Gu, Seoul, Republic of Korea
¹Department of Electrical Engineering, Seoul National University, San56-1,Sillim-dong Gwanak-Gu, Seoul, Republic of Korea

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Macroporous polymer beads have been used in various fields, for example as solid supports in solid-phase organic synthesis and heterogeneous catalysts and as adsorbents in column chromatography. Their broad applications have stimulated many researchers to develop various kinds of macroporous polymer beads. However, despite all the efforts, it is still hard to control the porosity and pore size distributions within the polymer beads. In this study, we prepared pore size controllable macroporous poly(methyl methacrylateco-methyl methacrylic acid) (PMMA-co-PMAA) beads. First, we prepared silica submicron particles embedded PMMA beads by the polymerization of methyl methacrylate monomer with mono-dispersed silica particles. Then, the silica NP embedded PMMA beads were hydrolyzed with sodium hydroxide to obtain a macroporous structure by removing the embedded silica particles. At the same time, part of the methyl methacrylate turned into methacrylic acid, which caused the PMMA beads to become PMAA-co-PMMA beads. Through this method, two types of beads having different pore sizes were prepared as a model study. The pore size of the beads could be easily controlled by adjusting the size of the silica particles.

Keywords:Porous polymer beads;Macroporous polymer;Silica particles;PMMA beads

[References]

Fruchtel JS, Jung G, Angew G, Chem. Int. Ed. Engl., 35, 17 (1996)
Madihally SV, Matthew HWT, Biomaterials., 20, 1133 (1999)
Lee DH, Kim JH, Jun BH, Kang H, Park J, Lee YS, Org. Lett., 10, 1609 (2008)
Deleuze H, Maillard B, Mondain-Monval O, Bioorg. Med. Chem. Lett., 12, 1877 (2002)
Jun BH, Byun JW, Kim JY, Kang H, Park HJ, Yoon J, Lee YS, J. Mater. Sci., 40, 3106 (2010)
Brown EC, Wilke SK, Boyd DA, Goodwin DG, Haile SM, J. Mater. Chem., 20, 2190 (2010)
Kim JW, Suh KD, J. Ind. Eng. Chem., 14(1), 1 (2008)
Lee SY, Chun YN, Kim SI, J. Ind. Eng. Chem., 15(3), 323 (2009)
Kim TY, Kim SJ, Yang JH, Cho SY, J. Ind. Eng. Chem., 10(2), 201 (2004)
Svec F, Frechet JM, Science, 273(5272), 205 (1996)
McCusker LB, Liebau F, Engelhardt G, Pure Appl. Chem., 73, 381 (2001)
Kangwansupamonkon W, Damronglerd S, Kiatkamjornwong S, J. Appl. Polym. Sci., 85(3), 654 (2002)
Liu QQ, Wang L, Xiao AG, Yu HJ, Tan QH, Eur. Polym. J., 44, 2516 (2008)
Wang Z, Kiesel ER, Stein A, J. Mater. Chem., 18, 2194 (2008)
Stein A, Microporous Mesoporous Mater., 44, 227 (2001)
Jiang P, Hwang KS, Mittleman DM, Bertone JF, Colvin VL, J. Am. Chem. Soc., 121(50), 11630 (1999)
Jang J, Lim B, Adv. Mater., 14(19), 1390 (2002)
Lepine O, Birot M, Deleuze H, Macromol. Mater. Eng., 294, 599 (2009)
Hu XB, An Q, Li GT, Tao SY, Liu B, Angew. Chem. Int. Ed., 45, 8145 (2006)
Brun N, Prabaharan SRS, Morcrette M, Sanchez C, Pecastaings G, Derre A, Soum A, Deleuze H, Birot M, Backov R, Adv. Funct. Mater., 19(19), 3136 (2009)
Kim SH, Heo CJ, Lee SY, Yi GR, Yang SM, Chem. Mater., 19, 4751 (2007)
Kim SH, Cho YS, Jeon SJ, Eun TH, Yi GR, Yang SM, Adv. Mater., 20(17), 3268 (2008)
Stober W, Fink A, Bohn E, J. Colloid Interface Sci., 26, 62 (1968)
Freris I, Cristofori D, Riello P, Benedetti A, J. Colloid Interface Sci., 331(2), 351 (2009)

[Referenced By]

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[1] Fruchtel JS, Jung G, Angew G, Chem. Int. Ed. Engl., 35, 17 (1996)

[2] Madihally SV, Matthew HWT, Biomaterials., 20, 1133 (1999)

[3] Lee DH, Kim JH, Jun BH, Kang H, Park J, Lee YS, Org. Lett., 10, 1609 (2008)

[4] Deleuze H, Maillard B, Mondain-Monval O, Bioorg. Med. Chem. Lett., 12, 1877 (2002)

[5] Jun BH, Byun JW, Kim JY, Kang H, Park HJ, Yoon J, Lee YS, J. Mater. Sci., 40, 3106 (2010)

[6] Brown EC, Wilke SK, Boyd DA, Goodwin DG, Haile SM, J. Mater. Chem., 20, 2190 (2010)

[7] Kim JW, Suh KD, J. Ind. Eng. Chem., 14(1), 1 (2008)

[8] Lee SY, Chun YN, Kim SI, J. Ind. Eng. Chem., 15(3), 323 (2009)

[9] Kim TY, Kim SJ, Yang JH, Cho SY, J. Ind. Eng. Chem., 10(2), 201 (2004)

[10] Svec F, Frechet JM, Science, 273(5272), 205 (1996)

[11] McCusker LB, Liebau F, Engelhardt G, Pure Appl. Chem., 73, 381 (2001)

[12] Kangwansupamonkon W, Damronglerd S, Kiatkamjornwong S, J. Appl. Polym. Sci., 85(3), 654 (2002)

[13] Liu QQ, Wang L, Xiao AG, Yu HJ, Tan QH, Eur. Polym. J., 44, 2516 (2008)

[14] Wang Z, Kiesel ER, Stein A, J. Mater. Chem., 18, 2194 (2008)

[15] Stein A, Microporous Mesoporous Mater., 44, 227 (2001)

[16] Jiang P, Hwang KS, Mittleman DM, Bertone JF, Colvin VL, J. Am. Chem. Soc., 121(50), 11630 (1999)

[17] Jang J, Lim B, Adv. Mater., 14(19), 1390 (2002)

[18] Lepine O, Birot M, Deleuze H, Macromol. Mater. Eng., 294, 599 (2009)

[19] Hu XB, An Q, Li GT, Tao SY, Liu B, Angew. Chem. Int. Ed., 45, 8145 (2006)

[20] Brun N, Prabaharan SRS, Morcrette M, Sanchez C, Pecastaings G, Derre A, Soum A, Deleuze H, Birot M, Backov R, Adv. Funct. Mater., 19(19), 3136 (2009)

[21] Kim SH, Heo CJ, Lee SY, Yi GR, Yang SM, Chem. Mater., 19, 4751 (2007)

[22] Kim SH, Cho YS, Jeon SJ, Eun TH, Yi GR, Yang SM, Adv. Mater., 20(17), 3268 (2008)

[23] Stober W, Fink A, Bohn E, J. Colloid Interface Sci., 26, 62 (1968)

[24] Freris I, Cristofori D, Riello P, Benedetti A, J. Colloid Interface Sci., 331(2), 351 (2009)