The effect of Na addition to PtSn/AlSBA-15 on the catalytic properties in propane dehydrogenation was studied. The catalysts were characterized by XRF, BET, HR-TEM, NH3-TPD, TPO and TPR. Results showed that the presence of sodium could not only modify the acid function of the catalysts but also the structure of metallic phase, thus reduce the amount of coke deposition. Among the catalysts investigated, PtSnNa (1.0%)/AlSBA-15 had the best catalytic performance in terms of propane conversion and stability. The high catalytic performance may be owing to the strong interaction between metal and support.