The kinetics of the gas-phase reactions of chlorine atoms with bromoethane (C2H5Br) and D-bromoethane (C2D5Br) was studied experimentally. The relative rate method was applied using Cl + C2H6 as the reference reaction. The rate constants for H-abstraction from C2H5Br (k(H)) and D-abstraction from C2D5Br (k(D)) were measured in the temperature range of 298-527 K and at a total pressure of 100 Torr using N-2 as a diluent. The temperature dependencies of the rate constants are described by the expressions: kH = (2.6 +/- 0.3) x 10(-11) x exp(-390 +/- 35/T) and k(D) = (2.8 +/- 0.2) x 10(-11) x exp(-750 +/- 30/T) cm(3) molecule(-1) s(-1). The kinetic isotope effect, described by the ratio k(H)/k(D), was found to be 3.2 at room temperature. (C) 2011 Elsevier B.V. All rights reserved.