The number of biogas injection plants is increasing. In Germany, the requirements for biogas injection are specified by DVGW G 260 and G 262. The most applied biogas upgrading technologies are the pressure swing adsorption and physical as well as chemical scrubbers. However, these technologies are usually not adapted to the particular injection parameters of a specific location. In this work the influences of pressure, temperature and further parameters are shown for the water and the Genosorb scrubber. For the simulations the software Aspen Plus was applied, and measurements are used for verification.