Contacting and separation of immiscible fluids in chemical synthesis is important for both reaction step as well as the post processing procedure. The importance of microstructured devices is due to their potential to provide short diffusion paths and high specific surfaces. In contrast to apparatus for single phase applications, which have been studied broadly, systematical research on microstructured dispersing devices and separators is still at its beginning. This paper focuses on the suitability of selected micromixers and hydrocyclons for multiphase applications.