Chemistry Letters, Vol.40, No.6, 632-634, 2011
Total Synthesis of Doubly Locked 5Za15Ea-Biliverdin Derivative: A Convergent Synthesis of the E-anti Dipyrrole Component Locked with a 7-Membered Ring
Doubly locked 5Za15Ea-biliverdin (BV) derivative was synthesized toward the investigation of stereochemistry and function of the Pfr-form chromophore in bacteriophytochromes. A convergent synthetic method was established for the locked E-anti dipyrrole component with a 7-membered ring.