Chemistry Letters, Vol.40, No.9, 1047-1049, 2011
Synthesis of Phenanthridinones and Phenanthridine Derivatives through Palladium-catalyzed Oxidative C-H Coupling of Benzanilides
A palladium-catalyzed oxidative C-H coupling reaction of benzanilides using molecular oxygen as the oxidant furnishes phenanthridinones. The palladium-catalyzed reaction in combination with simple derivatization provides an efficient access to a phenanthridine skeleton starting from readily available benzoic acids and anilines.