A pilot-scale biomass-gasification-reforming system (feedstock of 150-300 kg/h, on a dry basis) was established to produce synthesis gas for liquid fuel synthesis. The design and operation of this-system were preliminarily discussed. Reforming of biomass raw fuel gas over NiO-MgO/gamma-Al2O3/cordierite monolithic catalysts was investigated in a multi tube reformer. The anti coking and anti-sintering properties of NiO-MgO/gamma-Al2O3/cordierite monolithic catalysts were Characterized. The results showed that the NiO-MgO/gamma-Al2O3/cordierite monolithic catalyst with a pore channel size of 7 x 7 mm could continuously deal with biomass raw fuel gas containing large amounts of fly ash. NO channel blocking was observed for a long time running. The pressure drop, of the reformer was only below 700 Paeven under the conditions of fuel gas velocity of 1.4 m/s and fly ash content of 330 g N-1 m(-3) in the raw fuel gas. The synthesis gas [H-2 + CO > 60 vol %, H-2/CO ratio = 0.9-1.0, and lower heating value (LHV) > 10 MJ N-1 m(-3)], could be produced by the biomass-gasification-reforming process under the conditions of total equivalence ratio (ERT) of 0.27 (ERfirst of 0.23, ERsecond of 0.02, and ERthird of 0.02) and steam/biomass (S/B) ratio of 0.4. The cold gas efficiency was above 82%. The characterization of the spent catalysts thermogravimetic (TG), X-ray diffraction (XRD), and inductively coupled plasma-atomic emission spectrometry (ICP-AES) analyses indicated that the NiO-MgO solid solution structure in the catalyst could restrain the active Ni-0 centers from agglomeration and decrease carbon deposition. No serious alkali compound deposition on the surface of the catalyst was detected after the 60 h time-on-stream test. The pilot-scale biomass-gasification-reforming system exhibited excellent operation stability and flexibility.