The temperature and humidity independent control (THIC) system, which controls indoor temperature and moisture separately, may be an attractive alternative to existing conventional HVAC systems for its prominent improvement on the overall system performance and utilization of low grade energy resources. In order to verify the effectiveness of THIC system, a pilot project has been implemented in an office building in Shenzhen, China. In the system, liquid desiccant fresh air handling units driven by heat pumps are utilized to remove the entire latent load of outdoor air supplied for the whole building, and chilled water at the temperature of 17.5 degrees C from chiller is pumped and distributed into dry fan coil units and radiant panels to control indoor temperature. This paper presents the results of field test of the system, which shows that the system can provide a comfortable indoor environment even in very hot and humid weather. The COP of the entire THIC system can reach 4.0. According to the energy usage data recorded from the year 2009, the energy consumption of the THIC system in the tested office building was 32.2 kWh/(m(2) yr), which demonstrates magnificent energy-saving potential compared with the conventional air-conditioning system (around 49 kWh/(m(2) yr)). (C) 2011 Elsevier B.V. All rights reserved.