A series of comparative laboratory-scale experiments were carried out in the Lhasa plateau and the Hefei plain respectively to investigate the characteristics of flame spread over the extruded polystyrene (XPS) foam, a typical thermal insulation material. Flame shape and the temperature profile in solid phase were monitored, and the effects of altitude on the heat transfer process were analyzed. The results show that the temperature rise with time undergoes three stages: the preheating stage, the melting stage and the pyrolysis stage. The durations of the melting and pyrolysis stages on plateau are longer than that in plain, which sequentially results in a lower flame spread rate on plateau. Comparing of the temperature change rate curve on plateau with that in plain, it is found that the peak characteristics of the curves in the pyrolysis stage changed from single peak to multi-peaks, which suggests that the altitude difference might change the pyrolysis mechanisms of XPS material. Moreover, the sample scale effects on flame spread are also explored. Two different regimes are found in flame spread behavior with sample scale at the both altitudes. The spread rate drops with sample scale in convection regime and rises in radiation regime. (C) 2011 Elsevier B.V. All rights reserved.