Hot compression tests of the commercial Inconel 625 were performed in the temperature range of 950-1200 A degrees C and strain rate range of 0.01-10 s(-1). The flow behavior and processing maps were investigated using the corrected flow stress data to eliminate effects of the friction and adiabatic heating. The processing maps have exhibited a domain in the temperature range of 1100-1200 A degrees C and strain rate range of 0.01-10 s(-1) corresponding to the higher efficiency of power dissipation. Microstructural observations reveal that the full dynamic recrystallization (DRX) occurs in this domain, which is optimum processing window for hot working to obtain a homogeneous microstructure. DRX grain growth occurs in the temperature range of 1150-1200 A degrees C and strain rate range of 0.01-0.1 s(-1). In view of the refined and uniform grains obtained by hot deformation, the finish forming processing should be selected the deformation conditions in which the full DRX occurs without the grain growth. The small regimes of flow instability are noticed at temperature below about 970 A degrees C at the different strains. The material undergoes flow instability manifesting as bands of flow localizations and high density deformation twins. In addition, it is found that the undissolved second-phase particles and carbides can promote the DRX processing and be helpful to restrict the DRX grain growth.