Grafted poly(beta-glucan) (beta-glu) strands on the surface of silica are synthesized with varying degrees of grafting density, and display an amorphous-like environment via (13)C CP/MAS NMR spectroscopy. Thermal gravimetric analysis of these materials under oxidative conditions shows increased beta-glu thermal stability with higher degrees of grafting density. The range of temperature stability between the most and least hydrogen-bound grafted beta-glu strands spans 321 to 260 degrees C. This range is bound by the combustion temperature previously measured for crystalline and amorphous cellulose, with the former having greater oxidative stability, and is likely controlled by the extent of hydrogen bonding of a grafted beta-glu strand with the underlying silica surface. When using these materials as reactants for glycosidic bond hydrolysis, the total number of reducing ends formed during reaction is quantified using a BCA colorimetric assay. Results demonstrate that the material with greatest interaction with silica surface silanols undergoes hydrolysis at an initial rate that is 6-fold higher than the material with the lowest degree of such interaction. The role of the surface as a reactive interface that can endow oxidative stability and promote hydrolysis activity has broad implications for surface-catalyzed processes dealing with biomass-derived polymers.