We report the preparation of acrylic monomers D- or L-mono-(6-phenylalanine-acrylamido-6-deoxy)-beta-cyclodextrin 3(D)/3(L) and their corresponding copolymers 4(D)/4(L) bearing NIPAAm and D- or L-phenylalanine as guest and beta-cyclodextrin as host moieties. To implement the cyclodextrin resin (CD) into the monomer, microwave accelerated cycloaddition (click-reaction) was performed. For the new design of polymers having both host and guest species in the polymer side chain, inter- and intramolecular interactions could be observed. The resulting supramolecular structures were characterized by NMR, DLS, TEM, and LCST measurements.