(Bio)degradable poly(ester-urethane)s containing polylactide (PLA) and poly[(1,4-butylene terephthalate)-co-(1,4-butylene adipate)1 (BTA) segments in the main chain were synthesized and their properties were examined. Novel poly(ester-urethane)s were obtained from isophorone diisocyanate (IPDI), synthetic PLA-diol and/or synthetic BTA-diol oligomers in a two-step process. PLA-diol and BTA-diol oligomers were received via glycolysis of their respective polymers: PLA and BTA. Butanediol (BD) was used as a polymer chain extender. The synthesized poly(ester-urethane)s were characterized by DSC, NMR. GPC, MR and X-ray methods. The poly(ester-urethane)s that were examined had a single glass transition temperature (T(g)), which pointed to a one-phase system. The biodegradability of the received poly(ester-urethane)s was examined under industrial composting conditions. The results prove the possibility of synthesizing new perspective application materials, surrendering (bio)degradation in the environment. (C) 2011 Elsevier Ltd. All rights reserved.