Mixed semiconductor (CdS-ZnS)TiO2(1 : 1 : 1) mixture system over different supports like MgO, CaO, gamma-Al2O3, SiO2 and modified MgO and CaO, have been prepared, characterized and tested for H-2 production in a S2-/SO32- mixture solution. (CdS ZnS)-TiO2(D) over MgO support wherein the TiO2 taken is from Degussa (D) sample gives 206.7 mu mol/h of H-2 production and this catalyst sustain the H-2 production rate for longer durations. Dopants like Li2O Cs2O or K2O make MgO and CaO supports act like super basic oxide when they are doped and in turn increase the photocatalytic activity. The (CdS-ZnS)-TiO2(I) system wherein the TiO2 taken from Titanium Isopropoxide, supported on 20 wt% Li2O doped CaO is found to give 209.8 mu mol/h rate of H-2 production. Characterization studies like UV-Visible spectra, X-ray Diffraction spectra and Scanning Electron Microscope photographs were taken for all the catalysts and the data generated over these samples is evaluated. A scheme of H2S photocatalytic decomposition of ZnCdS-TiO2(D/I) over different supports in the presence of S2-/SO32- substrate, is proposed indicating the formation of thiosulfate cycle at this heterojunction.