A mathematical model for air-liquid two-phase flow in rotating packed beds (RPB) is established to describe the real condition of the fluid flow in the RPB. Results show that the model can better and reasonably predict the distribution of the air-liquid two-phase flow field, the pressure drop, the liquid film thickness, the proportion of the turbulent flow in the liquid film and some other complex hydrodynamic characteristics in the RPB. The results provide a theory basis for the, gas-liquid two-phase heat transfer and mass transfer.