In this study, Ti substrate was coated by three different mixed oxides (SnO2-Sb2O5, RuO2-TiO2, IrO2-Ta2O5), then PbO2 was electrodeposited on them to prepare PbO2 electrode. The microstructure of the solid solution interlayers and PbO2 coatings was characterized by scanning electronic microscopy and X-ray diffraction. The results indicated that the above oxides interlayer exited in the form of solid solution and the interlayer covered the Ti substrate largely. Accelerated life test proved that the presence of solid solution interlayer can increase the stability of PbO2 electrodes in electrolysis. Cyclic voltammogram indicated that the PbO2 electrode with the solid solution interlayer have more active surface area in sulfuric acid solution. Linear scanning voltammograms showed that the over potentials of the oxygen evolution are decreased with the addition of the solid solution interlayer. Electrochemical impedance spectroscopy showed that the presence of interlayer can increase the electrochemical activity of oxygen evolution reaction and electrical conductivity.