The impaction of water droplets on isothermal cylindrical wires has been investigated experimentally in the present study. Mono-size droplets of 110, 350 and 680 mu m in diameter were generated using piezoelectric droplet generators. The effects of droplet velocity and wire size were varied parametrically to reveal the impacting phenomena. Typical modes of the impaction outcome are disintegration and dripping. For droplets impacting on small wires, finer drops are disintegrated if the impacting droplet velocity is high, and larger dripping drops are observed if the velocity is low. For droplets impacting on large wires, bigger pendent drops are gradually formed which would eventually detach from the wires under the influence of gravity. In addition, droplets impacting on wires with waxy surface generate smaller dripping drops than that of the non-waxed wires. A non-dimensional regime map and new formulations in terms of the droplet Weber number, the wire Bond number and the size ratio of the wire diameter to incoming droplet diameter have been established to identify the regime for each mode of outcome and to predict the size of the dripping drops within the experimental limits.