Ordered TiO2/(La,Sr)MnO3 composite nanorod array catalysts have been successfully fabricated by using a combination of hydrothermal synthesis and radio-frequency (RF) magnetron sputtering method on Si and glass substrates. Electron microscopy, energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), and Brunauer-Emmett-Teller (BET) method are used to characterize the structure, morphology, composition and surface area of the as-prepared nanorod arrays. The TiO2/(La,Sr)MnO3 core-shell nanorod arrays exhibit an enhanced CO oxidation activity compared to TiO2 nanorods, which might be due to the lattice oxygen in (La,Sr)MnO3. The TiO2/(La,Sr)MnO3 composite nanorod array may provide a promising class of nanocatalysts for energy and environment applications. (C) 2011 Elsevier B.V. All rights reserved.